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MYASTHENIA GRAVIS AND THYMECTOMY

TREATMENT FOR MG

Drugs

Anti-Acetylcholinesterase Agents allow acetylcholine to remain at the neuromuscular junction longer than usual so that more receptor sites can be activated.

Corticosteroids And Immunosuppressant Agents may be used to suppress the abnormal action of the immune system that occurs in MG.

Surgery

Thymectomy (surgical removal of the thymus gland)is another treatment. Thymectomy may lessen the severity of the MG weakness after some months to years.

In some people the weakness may completely disappear. This is called a remission.The degree to which the thymectomy helps varies with each patient.

Other Measures

Plasmapheresisor plasma exchange is removal of the abnormal antibodies from the plasma of the blood.Plasmapheresis may be especially useful during severe MG weakness or prior to surgery.

Intravenous immune globulins (IVIg) are sometimes used to affect the function or the production of the abnormal antibodies.

Newer treatments with monoclonal antibodies (rituximab, eculizumab) may be available in the near future as another tool in the treatment of MG.




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